Genomes are the ultimate biological information medium, carrying the key instructions for every organism's development, life-cycle, and reproduction. In this course we will study genomes from a bioinformatics perspective. We will cover advances in our understanding of biology that have resulted from recent sequencing of the human and dozens of related organisms. Topics will include: (1) genome sequencing: technologies, assembly, personalized sequencing; (2) functional landscape: genes, regulatory modules, repeats, RNA genes, epigenetics; (3) genome evolution: evolutionary processes, comparative genomics, ultraconservation, exaptation. As time permits, we may cover population genetics and personalized genomics, ancient DNA, metagenomics, or other current topics.

Date	Subject
9/25	Introductory Biology Primer
10/2	Introduction to Text Processing
10/9	UCSC Genome Browser Tools